
Taking capsules or tablets with little or no water, or swallowing them lying down may have undesirable effects.
A study noted that in 4o percent of patients taking capsules lying down, the pills stay in the throat until they disintegrate. In patients with throat problems caused by other illnesses, such as mitral valve disease and old age, both capsules and tablets move more slowly.
A drug delayed in the throat may lead to adverse conditions such as ulcerations, stricture and suffocation.
Ulcerations are caused by more than 20 drugs, the most common of which are antibiotics and cardiac drugs. Rheumatism and arthritis medications can also damage the throat.
Slow transit of drugs through the throat also delays absorption. This delay could be significant in cases where rapid absorption is necessary, as with analgesics or pain relievers.
The Consumer's Association of London, in an article published in MD: A Journal for Doctors and condensed by Clubnews of Diners Club, suggests that patients should generally take capsules and tablets while standing or sitting upright. A liquid preparation should be considered for patients unable to do so.